Similac Or Enfamil: Which Formula Is The Right One For Your Baby?

Overview

Different formula brands offer various products to meet each baby’s specific nutrition requirements. Finding the best formula can be a big challenge for many parents, but some stick to popular name brands like Similac or Enfamil.

Still, there’s no perfect formula that can meet the needs of all children.

In choosing the right formula for your little one, you have to consider its ingredients and other contents versus what your baby needs and possible food sensitivities or allergies.

Similac uses more added sugars in your baby’s formula. It may be a more budget-friendly option but Enfamil has more natural ingredients and less sugar. For many moms, that can be the deciding factor.

So, what formulas do Similac and Enfamil offer? Are there special formula options for specific medical conditions? Which formula should you pick for your baby? Are there any formula recalls on these products? Find out below.

But make sure you consult with your little one’s pediatrician, no matter which brand or type of formula you pick for your child.

Also read up on whether toddler formulas are necessary here.

Bestsellers

Enfamil Favorites

Enfamil Nutramigen with Enflora LGG Powder Infant Formula

Enfamil NeuroPro Gentlease Infant Formula

Enfamil ProSobee Infant Formula

Similac Favorites

Similac Advance Infant Formula

Similac Pro-Sensitive Infant Formula

Similac NeoSure

Enfamil Products

Everyday Nutrition

Special Dietary Needs

Cow’s Milk Allergies & Other Food Allergies

Tummy Troubles (Gas, Fussiness, Crying, Colic, Or Spit-Up)

For Premature Babies

Other Special Formulas

Similac Products

Everyday Nutrition

- Similac 360 Total Care Infant Formula
- Similac Advance Infant Formula

- Similac Pro-Advance Infant Formula

Special Dietary Needs

For Premature Babies

Similac NeoSure Infant Formula

Tummy Troubles (Gas, Fussiness, Crying, Colic, Or Spit-Up)

Cow’s Milk Allergies & Other Food Allergies

Similac Alimentum Hypoallergenic Infant Formula
Similac EleCare

Other Special Formulas

Similac Advance Lamehadrin (Badatz Kosher certified formula, a special kosher certificate)

Enfamil Vs Similac: Main Similarities & Differences

Similarities

Pros

Both brands offer a wide range of infant products, including non-dairy, lactose-free, soy-based, or hypoallergenic formulas. (1-4)
Both have non-GMO formulas.
GMOs (genetically modified organisms) may cause autoimmunity, allergies, neurological disorders, autism, ADHD (attention deficit hyperactivity disorder), endocrine disruption, and growth failure. (5)
Both brands meet the infant formula requirements of the FDA (Food and Drug Administration) and may be safe for babies. (6)
Both brands contain choline, a nutrient that can help metabolize or digest fats (7)
Both have vitamin K, an important vitamin for bone metabolism that may also have anti-cancer effects (8)
Both contain DHA (docosahexaenoic acid), lutein, and vitamin E, which can support your baby’s brain and eye development (9)(10)(11)
Both have ARA (arachidonic acid), which is a special nutrient found in breast milk that can promote a healthier immune system, and muscle repair and growth (9)
Most formulas also contain taurine (may play a role in brain development) and nucleotides (may promote immune response) (12)(13)
Loyalty programs: Enfamil Family Beginnings Program and Similac StrongMoms Rewards

Cons

Most of the products from both brands contain soy oil. Although highly refined soy oil may be allergen-free, you might still want to keep an eye on this ingredient, especially if your child has soy allergies. (14)
They contain processed vegetable oils, which can contain unhealthy trans fats that may lead to a higher risk of developing coronary heart diseases (15)
Most products are non-organic
These formulas can still be safe for consumption, but some parents prefer organic formulas, which may be a healthier alternative.
Organic formulas and foods may have the same nutritional values as non-organic options. But they may reduce the risk of eczema in infants, obesity, and certain cancers, such as non-Hodgkin lymphoma. (16)

Differences

Between the two brands, the different products also have different features. But these are their main differences:

Enfamil Highlights

May use less sugar

Similac Highlights

Most Similac formulas cost less than Enfamil (when comparing similar products)
Usually has higher levels of linoleic acid
Studies show that this fatty acid may help promote growth and development, especially in preterm babies. (17)
Similac formulas may be free from palm olein oil, a common ingredient in formulas that can reduce calcium absorption. (18)

Similac Vs. Enfamil: Comparison Of Similar Products

Flagship Formulas

Basic milk products that can provide nutrition for your baby in the first year of their life
Milk-based ingredients (whey protein, lactose, and nonfat milk)
Similar mixture of oils (coconut oil, soy oil, and high oleic safflower oil).
Prebiotics, which can help promote a healthy gut (19)
Free from added sugars, maltodextrin, and corn syrups (20)(21)

Enfamil Infant Highlights

Contains two types of prebiotics; Similac Advance has only one
Doesn’t have a recall
More carbohydrates, folic acid, and vitamin E

Similac Advance Highlights

Cheaper than Enfamil Infant
More proteins, fats, and linoleic acid

Formulas For Spit-Up

Formulated for babies who may spit up a lot
Rice starch for a thicker formulation

Enfamil A.R. Highlights

Free from corn syrup and added sugars
Dual prebiotics for better gut health (19)
More carbohydrates, proteins, folic acid, and vitamins D and E

Similac for Spit-Up Highlights

Costs less than Enfamil A.R.
Non-GMO formula
More fat content, calcium, and linoleic acid

Gentle Formulas

Formulated for fussiness and gas
Both contain corn syrup solids

Enfamil NeuroPro Gentlease Highlights

MFGM (milk fat globule membrane), which can promote neurodevelopment and defense against infections (22)
More proteins, folic acid, and vitamin E

Similac Pro-Sensitive Highlights

Costs less than Enfamil Neuropro Gentlease
Prebiotics for a healthier gut (19)
More fat content, carbohydrates, calcium, and linoleic acid

Formulas For Babies With Allergies

Formulated for babies with hypersensitivities or allergies to proteins in cow’s milk formula
Casein hydrolysate (smaller, broken-down proteins)

Enfamil Nutramigen Highlights

The brand claims that it can reduce the incidence of future allergies (such as asthma and allergic rhinitis) and may help your baby overcome a cow’s milk allergy.
Probiotics or friendly gut bacteria (23)
More carbohydrates, protein equivalent, folic acid, and choline

Similac Alimentum Highlights

Costs less than Enfamil Nutramigen
MCT oils (medium-chain triglycerides) that may be easier to absorb (24)
More calcium, total fats, vitamin E, and linoleic acid

Formula For Premature Babies

Formulated for premature babies
Easy-to-digest milk-based formulas
Can promote better immune health
Free from palm oil, which can affect calcium absorption (18)

Enfamil NeuroPro Highlights

MFGM (milk fat globule membrane), which can promote brain development and a healthier immune system (22)
More carbohydrates, calcium, folic acid, choline, linoleic acid, and vitamins A, D, and E

Similac Neosure Highlights

Costs less than Enfamil NeuroPro
Free from artificial growth hormones (25)
More fat content

Lactose-Free, Non-Dairy Soy Formulas

Lactose-free soy proteins
Formulated for babies with milk protein allergies
May be given to babies with galactosemia (a condition that prevents your baby’s body from properly digesting the simple sugar galactose, a component of larger sugar lactose) (4)
Alternative formulas if your baby’s tummy is sensitive to milk proteins
Corn syrup

Enfamil ProSobee Highlights

More carbohydrates, proteins, folic acid, and vitamin E

Similac Soy Isomil Highlights

Costs less than Enfamil ProSobee
Prebiotics for a healthier immune system (19)
More fat content and linoleic acid

Learn more about each formula below.

Flagship Formulas: Enfamil Infant Vs. Similac Advance

Enfamil Infant Formula

Best Features & Safety

Complete nutrition for your baby’s first year
Choline and DHA (docosahexaenoic acid), which are important nutrients for your baby’s brain development (9)
Dual-prebiotics blend (galactooligosaccharides and polydextrose) to support your baby’s immune system (19)
Free from added sugars, maltodextrin, and corn syrups.

Product Recall

None

Cons

Palm olein oil, soy oil, and other questionable processed vegetable oils (14)(15)(18)
Potential allergens: soy lecithin and milk (2)(26)

Ingredients

Nonfat milk
Lactose
Vegetable oil (palm olein, soy, coconut, and high oleic sunflower oils)
Whey protein concentrate
GOS (galactooligosaccharides) prebiotics
Polydextrose prebiotics
Mortierella alpina oil (ARA source)
Crypthecodinium cohnii oil (DHA source)
Lutein
Soy lecithin
Nucleotides
Taurine

Nutritional Facts

Each serving (5 fl oz, 100 calories) contains:

Total fats: 5.3 g
Total carbohydrates: 11.3 g
Proteins: 2 g
Iron: 1.8 mg
Calcium: 78 mg
Folic acid: 16 mcg
Choline: 24 mg
Vitamin A: 300 IU
Vitamin D: 60 IU
Vitamin E: 2 IU
Linoleic acid: 800 mg

What Customers Say

“My daughter loves this milk… no issues at all and we are happy to have enfamil.” – Reviewer on Enfamil’s website.

“This gave my first daughter really bad acid reflux. Now its the same for my second daughter.” – Reviewer on Enfamil’s website.

Similac Advance Infant Formula

Best Features & Safety

Nutritionally complete, iron-fortified milk-based infant formula for your baby’s first year
Free from palm oil, which can reduce calcium absorption (18)
Blend of DHA, lutein, and vitamin E, which can support your baby’s brain and eye development (9)(10)(11)
Free from artificial growth hormones that may be linked to certain cancers. (25)
Kosher and halal
Prebiotic FOS (fructooligosaccharides) for a healthier immune system and gut health (19)
Free from added sugars, maltodextrin, and corn syrup

Product Recall

Similac Advance (powder formula) was included in the 2010 Similac recall due to the possible contamination with the small common beetle. (27)
According to the FDA’s recall advisory, ingesting the beetle larvae or insect parts may not pose a significant health risk. But it can cause intestinal discomfort, and your child might refuse to eat. (27)
In 2006, Similac Advance (liquid, ready-to-drink formula) was recalled because the bottles had a manufacturing defect. Due to a lacking layer in the bottle, the contents may react with air and have a reduced amount of vitamin C. (28)
In 2005, Similac Advance with Iron (powder formula) was also recalled due to the possible contamination with polyvinyl chloride plastic particles. It was attributed to a manufacturing issue. (29)

Cons

It had recalls.
Potential allergens: milk and soy
Soy oil and other processed vegetable oils

Ingredients

Nonfat milk
Lactose
High oleic safflower oil
Whey protein concentrate
Soy oil
Coconut oil
C. cohnii oil (DHA source)
M. alpina oil (ARA source)
Short-chain fructooligosaccharide prebiotics
Lutein
Soy lecithin
Taurine
Nucleotides

Nutritional Facts

Each serving (5 fl oz, 100 calories) contains:

Total fats: 5.6 g
Total carbohydrates: 10.5 g
Proteins: 2.07 g
Iron: 1.8 mg
Calcium: 78 mg
Folic acid: 15 mcg
Choline: 24 mg
Vitamin A: 300 IU
Vitamin D: 60 IU
Vitamin E: 1.5 IU
Linoleic acid: 1,000 mg

What Customers Say

“I love this milk because it does not cause cramps in my son.” – Reviewer on Similac’s website.

“It is difficult for baby to digest Similac Advance. Frequency increased for vometting whatever baby drinks.” – Reviewer on Similac’s website.

Formula for Spit-Up: Enfamil A.R. Vs. Similac for Spit-Up Infant Formula

Enfamil A.R.

Best Features & Safety

Complete nutrition for your baby’s first year
Enfamil claims that it’s clinically proven to reduce spit-up by more than 50% in one week.
DHA, which can help support your baby’s brain development (9)
Dual prebiotics (galactooligosaccharides and polydextrose), which may promote better digestive and immune health (19)
Meets reflux reduction guidelines (thickened formula) set by the AAP (American Academy of Pediatrics) (30)
Free from corn syrup and added sugars

Product Recall

None

Cons

Palm olein oil, soy oil, and processed vegetable oils (14)(15)(18)
Maltodextrin, which may cause colic, gas, bloating, green stools, and possible intestinal injury (20)
Potential allergen: milk (2)
Rice starch (used as a thickening agent); although starches are considered safe by the AAP, there’s public pressure to remove this ingredient from any baby food (31)

Ingredients

Nonfat milk
Vegetable oil (palm olein, soy, coconut, and high oleic sunflower oils)
Rice starch
Lactose
Maltodextrin
GOS (galactooligosaccharides) prebiotics
Polydextrose prebiotics
Mortierella alpina oil (ARA source)
Crypthecodinium cohnii oil (DHA source)
Taurine

Nutritional Facts

Each serving (5 fl oz, 100 calories) contains:

Total fats: 5.1 g
Total carbohydrates: 11.3 g
Proteins: 2.5 g
Iron: 1.8 mg
Calcium: 78 mg
Folic acid: 16 mcg
Choline: 24 mg
Vitamin A: 300 IU
Vitamin D: 60 IU
Vitamin E: 2 IU
Linoleic acid: 780 mg

What Customers Say

“Only thing my newborn is able to keep down without throw up/spit up!” – Reviewer on Enfamil’s website.

“I bought this for my daughter since she has acid reflux and it was recommended by her doctor and she was severely constipated to the point where she was throwing up from trying to go.” – Reviewer on Enfamil’s website.

Similac for Spit-Up Infant Formula

Best Features & Safety

The brand claims that it’s clinically proven to reduce spit-up frequency by 54% in healthy infants.
Non-GMO formula
Easy-to-digest formula that may be suitable for babies with lactose sensitivity
Exclusive blend of DHA, lutein, and vitamin E that may support your baby’s brain and eye development (9)(10)(11)
Free from palm olein oil, which can affect calcium absorption (18)
Free from artificial growth hormones (25)
Doesn’t have maltodextrin

Product Recall

None

Cons

Rice starch as a thickening agent; starches are considered safe by the AAP, but many are calling for its removal as an ingredient of baby food (31)
Soy oil and processed vegetable oils.
Added sugars and corn syrup
Potential allergen: milk

Ingredients

Corn syrup
Rice starch
Milk protein isolate
Sugar
High oleic safflower oil, soy oil, and coconut oil
GOS (galactooligosaccharides) prebiotics
C. cohnii oil (DHA source)
M. alpina oil (ARA source)
Lutein
Taurine
Nucleotides

Nutritional Facts

Each serving (5 fl oz, 100 calories) contains:

Total fats: 5.4 g
Total carbohydrates: 11 g
Proteins: 2.1 g
Iron: 1.8 mg
Calcium: 84 mg
Folic acid: 15 mcg
Choline: 24 mg
Vitamin A: 300 IU
Vitamin D: 50 IU
Vitamin E: 1.5 IU
Linoleic acid: 1,000 mg

What Customers Say

“Hallelujah, after buying this formula all the screaming stopped, we have one very content baby, no spitting up and longer uninterrupted naps, an absolute blessing.” – Reviewer on Similac’s website.

“It did reduce my 6 month old spit ups, but her bowl movements have reduced and she started gaining weight immediately. The weight gain may be due to the sugar ingredient.” – Reviewer on Similac’s website.

Gentle Formulas: Enfamil NeuroPro Gentlease vs. Similac Pro-Sensitive

Enfamil NeuroPro Gentlease Infant Formula

Best Features & Safety

Complete nutrition for your baby’s first year
The brand claims that this formula can provide all-in-one digestive comfort in 24 hours
May reduce fussiness, crying, gas, and spit-up
Easy-to-digest proteins
MFGM (milk fat globule membrane), which can promote neurodevelopment and defense against infections (22)
DHA and ARA, which can promote your baby’s brain development healthier immune system (9)
Free from added sugars and maltodextrin

Product Recall

None

Cons

Corn syrup, soy oil, palm oil, and processed vegetable oils

Ingredients

Corn syrup solids
Partially hydrolyzed nonfat milk
Whey protein concentrate solids (soy)
Vegetable oil (palm olein, soy, coconut, and high oleic sunflower oils)
Whey protein-lipid concentrate, a source of MFGM
Mortierella alpina oil (ARA source)
Schizochytrium sp. oil (DHA source)
Taurine

Nutritional Facts

Each serving (5 fl oz, 100 calories) contains:

Total fats: 5.3 g
Total carbohydrates: 10.8 g
Proteins: 2.3 g
Iron: 1.8 mg
Calcium: 82 mg
Folic acid: 16 mcg
Choline: 24 mg
Vitamin A: 300 IU
Vitamin D: 60 IU
Vitamin E: 2 IU
Linoleic acid: 780 mg

What Customers Say

“My son was very gassy and fussy in the beginning and we started using this and it has helped a lot.” – Reviewer on Enfamil’s website.

“This caused her to have way more spit up, more gass/fussiness and gray green colored poop.” – Reviewer on Enfamil’s website.

Similac Pro-Sensitive Infant Formula

Best Features & Safety

May help reduce fussiness or gas due to lactose sensitivity for babies with sensitive tummies
2’-FL HMO (human milk oligosaccharide), a prebiotic abundant in breast milk that may support your baby’s developing immune system (19)
DHA, lutein, and vitamin E blend to help promote your baby’s brain and eye development (9)(10)(11)
Free from palm olein oil, which can affect calcium absorption (18)
Free from artificial growth hormones
Non-GMO formula
Doesn’t have maltodextrin

Product Recall

None

Cons

Corn syrup, soy oil, and processed vegetable oils
Added sugars
Potential allergens: milk and soy lecithin

Ingredients

Corn syrup
Milk protein isolate
Sugar
High oleic safflower oil, soy oil, and coconut oil
C. cohnii oil (DHA source)
M. alpina oil (ARA source)
2’-fucosyllactose, short-chain fructooligosaccharides (prebiotics)
Lutein
Soy lecithin
Nucleotides

Nutritional Facts

Each serving (5 fl oz, 100 calories) contains:

Total fats: 5.4 g
Total carbohydrates: 10.9 g
Proteins: 2.1 g
Iron: 1.8 mg
Calcium: 84 mg
Folic acid: 15 mcg
Choline: 24 mg
Vitamin A: 300 IU
Vitamin D: 60 IU
Vitamin E: 1.5 IU
Linoleic acid: 1,000 mg

What Customers Say

“This is the only formula that works for my LO who is now 11 months old.” – Reviewer on Amazon.

“This particular similar formula has been awful for my baby. It gave her more gas, made her so fussy, and the poor thing could not sleep well EVER.” – Reviewer on Similac’s website.

Formula for Babies with Allergies: Enfamil Nutramigen vs. Similac Alimentum

Enfamil Nutramigen With Enflora LGG Powder Infant Formula

Best Features & Safety

Hypoallergenic formula made with extensively hydrolyzed (broken-down) proteins that may be less likely to trigger an allergic response
Lactose-free formula
The brand claims that it’s clinically proven to reduce colic because of cow’s milk allergy within 48 hours.
The brand also claims that this may help reduce the incidence of future allergies, such as asthma, eczema, allergic rhinitis, and hives.
According to the brand, this formula may also help your baby overcome a cow’s milk allergy and return to a regular formula within six months of feeding, compared with the Enfamil Nutramigen formula without Enflora LGG.
DHA and ARA, which are nutrients in breast milk that may support your baby’s brain and eye development (9)
Lactobacillus rhamnosus (probiotic cultures), which can promote a healthier gut (23)
Free from added sugars and maltodextrin

Product Recall

In 2001, Enfamil Nutramigen was recalled due to incorrect preparation instructions printed on the label. Following these instructions may lead to serious health problems, possibly even death. (32)(33)

Cons

It had a recall.
Corn syrup, palm oil, soy oil, modified corn starch, and processed vegetable oils

Ingredients

Corn syrup solids
Vegetable oil (palm olein, soy, coconut, and high oleic sunflower oils)
Casein hydrolysate (milk)
Modified corn starch
Mortierella alpina oil (ARA source)
Schizochytrium sp. oil (DHA source)
Lactobacillus rhamnosus (probiotic cultures)
Taurine

Nutritional Facts

Each serving (5 fl oz, 100 calories) contains:

Total fats: 5.3 g
Total carbohydrates: 10.3 g
Protein equivalent: 2.8 g
Iron: 1.8 mg
Calcium: 94 mg
Folic acid: 16 mcg
Choline: 24 mg
Vitamin A: 300 IU
Vitamin D: 60 IU
Vitamin E: 2 IU
Linoleic acid: 780 mg

What Customers Say

“I just started my 5 week old on this because we found out she had an cow allergy and it worked so fast . she stopped spitting up and being fussy.” – Reviewer on Enfamil’s website.

“My daughter started having really bad acid reflux and did not want to drink her bottles.” – Reviewer on Amazon.

Similac Alimentum

Best Features & Safety

Hypoallergenic formula for babies up to 12 months old with food allergies and colic symptoms due to protein sensitivity
The brand claims that it’s clinically proven to reduce excessive crying because of cow’s milk protein sensitivity within 24 hours.
Lactose-free formula
DHA and ARA, which are special nutrients found in breast milk that can support brain and eye development (9)
Broken-down proteins that may be easier to digest for babies with food allergies
MCT oils (medium-chain triglycerides), which may be easier to absorb and suitable for lactose sensitivity (24)
Free from palm olein oil, which can reduce calcium absorption (18)

Product Recall

In 2006, Similac Alimentum liquid ready-to-drink formula was recalled due to a missing layer in the bottle caused by a manufacturing error. The absence of this layer causes air to get in the bottle and react with its content, leading to a reduced vitamin C content. (28)

Cons

Added sugars, corn maltodextrin, soy oil, and processed vegetable oils
Xanthan gum; though JECFA (Joint FAO/WHO Expert Committee on Food Additives) considers it safe as a stabilizer to infant formula, it may cause gas, bloating, or flu-like symptoms (34)(35)
The liquid formulation had a recall

Ingredients

Corn maltodextrin
Casein hydrolysate (broken-down milk proteins) derived from milk
Sugar
High oleic safflower oil
Medium-chain triglycerides
Soy oil
C. cohnii oil (DHA source)
M. alpina oil (ARA source)
Xanthan gum
Taurine

Nutritional Facts

Each serving (5 fl oz, 100 calories) contains:

Total fats: 5.54 g
Total carbohydrates: 10.2 g
Protein equivalent: 2.75 g
Iron: 1.8 mg
Calcium: 105 mg
Folic acid: 15 mcg
Choline: 12 mg
Vitamin A: 300 IU
Vitamin D: 60 IU
Vitamin E: 3 IU
Linoleic acid: 800 mg

What Customers Say

“Alimentum is the only formula that my infant can tolerate due to both a milk protein allergy and a corn allergy.” – Reviewer on Similac’s website.

“My first impression was that this stuff smells really bad. I couldn’t tell you if this works or not because my baby HATED the taste.” – Reviewer on Walmart.

Formula for Premature Babies: Enfamil NeuroPro Enfacare vs. Similac NeoSure

Enfamil NeuroPro Enfacare

Best Features & Safety

Formulated for premature babies
Recommended for use up to nine months of age
The brand claims that it’s clinically proven to promote catch-up growth similar to full-term breastfed babies.
Milk-based formula with enriched nutrition from DHA and ARA to help support your baby’s immune system and brain development (9)
MFGM (milk fat globule membrane), which can also promote neurodevelopment and defense against infections (22)
Free from palm olein oil, which can reduce calcium absorption (18)

Product Recall

None

Cons

Maltodextrin, soy oil, and processed vegetable oils
Potential allergens: milk and soy lecithin

Ingredients

Water
Nonfat milk
Maltodextrin
Lactose
Whey protein concentrate
High oleic sunflower oil
Soy oil
MCT oil (medium chain triglycerides)
Whey
Protein-lipid concentrate
Coconut oil
Mortierella alpina oi (ARA source)
Schizochytrium sp. oil (DHA oil)
Soy lecithin
Carrageenan
Nucleotides
Taurine

This product contains carrageenan. Although there’s some public concern over this ingredient, OB-GYN and Maternal-Fetal Medicine Dr. Kecia Gaither and the FDA assure parents that it can be a safe additive to baby formula. (36)(37)

Nutritional Facts

Each serving (4.5 fl oz, 100 calories) contains:

Total fats: 5.3 g
Total carbohydrates: 10.4 g
Proteins: 2.8 g
Iron: 1.8 mg
Calcium: 120 mg
Folic acid: 26 mcg
Choline: 24 mg
Vitamin A: 450 IU
Vitamin D: 75 IU
Vitamin E: 4 IU
Linoleic acid: 780 mg

What Customers Say

“I got this when my premie weighed 4lb 11oz and within 3 days he went up to 5lb 6oz! It’s truly helped our little guy!” – Reviewer on Enfamil’s website.

“To harsh for my preemie, he threw up every time he was given enfacare for extra calories.” – Reviewer on Enfamil’s website.

Similac NeoSure

Best Features & Safety

May provide complete nutrition for babies born prematurely
More protein, vitamins, and minerals than standard infant formula to promote catch-up growth
Unique blend of DHA, lutein, and vitamin E that may support brain and eye development (9)(10)(11)
More calcium and phosphorus for your baby’s growing bones
Free from artificial growth hormones and palm olein oil (may reduce calcium absorption) (18)

Product Recall

None

Cons

Corn syrup, soy oil, and processed vegetable oils
Potential allergens: milk and soy lecithin

Ingredients

Nonfat milk
Corn syrup solids
Lactose
Soy oil
High oleic safflower oil
Whey protein concentrate
MCT oil (medium chain triglycerides)
Coconut oil
C. cohnii oil (DHA source)
M. alpina oil (ARA source)
Lutein
Soy lecithin
Taurine
Nucleotides

Nutritional Facts

Each serving (4.5 fl oz, 100 calories) contains:

Total fats: 5.5 g
Total carbohydrates: 10.1 g
Proteins: 2.8 g
Iron: 1.8 mg
Calcium: 105 mg
Folic acid: 25 mcg
Choline: 16 mg
Vitamin A: 350 IU
Vitamin D: 70 IU
Vitamin E: 3.6 IU
Linoleic acid: 750 mg

What Customers Say

“Helped him gain the weight he needed to leave the NICU after 6 days and come home.” – Reviewer on Similac’s website.

“Since we switched to neosure she is so uncomfortable and at times miserable and burns all the extra calories trying to pass gas and poop.” – Reviewer on Similac’s website.

Lactose-Free, Non-Dairy Soy Formula: Enfamil ProSobee vs. Similac Soy Isomil

Enfamil ProSobee

Best Features & Safety

Soy-based, lactose-free alternative to milk-based formulas
May help ease fussiness and gas caused by sensitivity to dairy-based formulas
Can be ideal for vegetarian or Kosher diets
Comparable amount of DHA as standard, dairy Enfamil formulas
DHA and ARA, which may help with your baby’s brain and immune system function (9)

Product Recall

None

Cons

Corn syrup, soy oil, palm olein oil, and processed vegetable oils
Potential allergen: soy protein

Ingredients

Corn syrup solids
Vegetable oil (palm olein, soy, coconut, and high oleic sunflower oils)
Soy protein isolate
Mortierella alpina oil (ARA source)
Crypthecodinium cohnii oil (DHA source)
Taurine

Nutritional Facts

Each serving (5 fl oz, 100 calories) contains:

Total fats: 5.3 g
Total carbohydrates: 10.6 g
Proteins: 2.5 g
Iron: 1.8 mg
Calcium: 105 mg
Folic acid: 16 mcg
Choline: 24 mg
Vitamin A: 300 IU
Vitamin D: 60 IU
Vitamin E: 2 IU
Linoleic acid: 800 mg

What Customers Say

“Love the product since we are vegetarian this was a good formula too use since I was not able to breastfeed my first baby.” – Reviewer on Enfamil’s website.

“Made my baby vomit all night. Do not recommended at all.” – Reviewer on Enfamil’s website.

Similac Soy Isomil

Best Features & Safety

Nutritionally complete soy-based formula that may be easier to digest by infants with sensitive tummies
May help relieve fussiness and gas
Special formula for babies with lactose intolerance and galactosemia (4)
The brand claims that it’s the only soy formula clinically proven to help support your baby’s developing immune system like dairy-based formulas.
Can be suitable for vegetarian diets
Prebiotic FOS (fructooligosaccharides) that may help support a healthy gut and immune system (19)
DHA, lutein, and vitamin E, which are special ingredients in breast milk that may support your baby’s brain and eye development (9)(10)(11)
Free from palm oil, which can reduce calcium absorption (18)

Product Recall

None

Cons

Corn syrup, soy oil, and processed vegetable oils
Added sugars

Ingredients

Corn syrup solids
Soy protein isolate
High oleic safflower oil
Sugar
Soy oil
Coconut oil
C. cohnii oil (DHA source)
M. alpina oil (ARA source)
Lutein
Short-chain fructooligosaccharides (prebiotics)
Taurine
Lycopene

Nutritional Facts

Each serving (5 fl oz, 100 calories) contains:

Total fats: 5.46 g
Total carbohydrates: 10.4 g
Proteins: 2.45 g
Iron: 1.8 mg
Calcium: 105 mg
Folic acid: 15 mcg
Choline: 24 mg
Vitamin A: 300 IU
Vitamin D: 60 IU
Vitamin E: 1.5 IU
Linoleic acid: 1,000 mg

What Customers Say

“I switched to this lactose free option 5 days ago and my baby has not spit up at all.” – Reviewer on Similac’s website.

“This formula did not work for our 4-month old as he would throw it all up about an hour after he ate it.” – Reviewer on Similac’s website.

Which One Is Better Similac Or Enfamil?

Choose Enfamil formulas if:

You prefer a brand with more natural ingredients and less sugar
You don’t mind the higher price tag

Choose Similac formulas if:

You prefer a more budget-friendly option
You don’t mind having more added sugars in your baby’s formula
You’re looking for products with higher levels of linoleic acid, which can promote growth and development, especially in preterm babies (17)
You prefer formulas free from palm olein oil so your baby can absorb more calcium necessary for bone development (18)

Formula FAQs

Why Is Similac Bad For You?

Because Similac is cheaper than Enfamil, it might seem like the better option.

But note that Similac may be using more sugars than Enfamil.

Corn syrup and other added sugars may increase your baby’s appetite and promote obesity. (21)

So, you should consider each formula’s ingredients and nutritional values before making your choice.

And be sure to also ask for your pediatrician’s approval before switching to any new formula.

Is It Bad To Switch From Similac To Enfamil?

Despite having some differences, formulas of the same type might have similar contents. So, switching between the brands might not make a huge difference, unless your child has sensitivities to the components of the other formula.

Still, it’s important to check with your pediatrician before making the switch.

REFERENCES

(1) https://www.mayoclinic.org/diseases-conditions/lactose-intolerance/symptoms-causes/syc-20374232

(2) https://www.mayoclinic.org/diseases-conditions/milk-allergy/symptoms-causes/syc-20375101

(3) https://kidshealth.org/en/parents/soy-allergy.html

(4) https://www.childrenshospital.org/conditions-and-treatments/conditions/g/galactosemia/symptoms-and-causes

(5) https://www.greenamerica.org/blog/downsides-gmo-infant-formula-we-asked-pediatrician

(6) https://www.fda.gov/food/people-risk-foodborne-illness/questions-answers-consumers-concerning-infant-formula

(7) https://ods.od.nih.gov/factsheets/Choline-HealthProfessional/

(8) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600246/

(9) https://pubmed.ncbi.nlm.nih.gov/29413359/

(10) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164534/

(11) https://kidshealth.org/en/kids/vitamin.html

(12) https://pubmed.ncbi.nlm.nih.gov/9635063/

(13) https://pubmed.ncbi.nlm.nih.gov/12410863/

(14) https://pubmed.ncbi.nlm.nih.gov/3894482/

(15) https://www.cfs.gov.hk/english/multimedia/multimedia_pub/multimedia_pub_fsf_85_01.html

(16) https://pubmed.ncbi.nlm.nih.gov/32519524/

(17) https://pubmed.ncbi.nlm.nih.gov/15825825/

(18) https://pubmed.ncbi.nlm.nih.gov/16582027/

(19) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615227/

(20) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940893/

(21) https://health.clevelandclinic.org/avoid-the-hidden-dangers-of-high-fructose-corn-syrup-video/

(22) https://pubmed.ncbi.nlm.nih.gov/27234413/

(23) https://www.healthychildren.org/English/ages-stages/baby/formula-feeding/Pages/Probiotics-in-Infant-Formula.aspx

(24) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209465/

(25) https://www.cancer.org/cancer/cancer-causes/recombinant-bovine-growth-hormone.html

(26) https://www.kidswithfoodallergies.org/soy-allergy.aspx

(27) https://www.reuters.com/article/us-abbott-idUSTRE68L4ZI20100922

(28) https://www.nytimes.com/2006/09/16/us/recall-of-infant-formula.html

(29) https://abcnews.go.com/Health/ParentingResourceCenter/similac-recall-bug-parts-baby-formula-worry-parents/story?id=11710959

(30) https://publications.aap.org/pediatrics/article/131/5/e1684/31266/Gastroesophageal-Reflux-Management-Guidance-for

(31) https://pubmed.ncbi.nlm.nih.gov/29762373/

(32) https://www.nytimes.com/2001/07/10/us/national-briefing-science-and-health-recall-of-baby-formula.html

(33) http://flca.info/HTMLobj-154/Recalls.pdf

(34) https://apps.who.int/food-additives-contaminants-jecfa-database/chemical.aspx?chemID=802

(35) https://www.npr.org/sections/health-shots/2011/05/23/136574547/fda-warns-against-food-thickener-for-premature-infants

(36) https://www.fda.gov/food/people-risk-foodborne-illness/questions-answers-consumers-concerning-infant-formula

(37) https://www.globenewswire.com/news-release/2019/02/07/1712386/0/en/Dr-Kecia-Gaither-Cautions-Mothers-on-Fables-and-Facts-with-Babies-Bottles-and-Booze.html

Overview

Bestsellers

Enfamil Favorites

Enfamil Nutramigen with Enflora LGG Powder Infant Formula

Enfamil NeuroPro Gentlease Infant Formula

Enfamil ProSobee Infant Formula

Similac Favorites

Similac Advance Infant Formula

Similac Pro-Sensitive Infant Formula

Similac NeoSure

Enfamil Products

Everyday Nutrition

Special Dietary Needs

Similac Products

Everyday Nutrition

Special Dietary Needs

Enfamil Vs Similac: Main Similarities & Differences

Similarities

Differences

Similac Vs. Enfamil: Comparison Of Similar Products

Flagship Formulas

Enfamil Infant Highlights

Similac Advance Highlights

Formulas For Spit-Up

Enfamil A.R. Highlights

Similac for Spit-Up Highlights

Gentle Formulas

Enfamil NeuroPro Gentlease Highlights

Similac Pro-Sensitive Highlights

Formulas For Babies With Allergies

Enfamil Nutramigen Highlights

Similac Alimentum Highlights

Formula For Premature Babies

Enfamil NeuroPro Highlights

Similac Neosure Highlights

Lactose-Free, Non-Dairy Soy Formulas

Enfamil ProSobee Highlights

Similac Soy Isomil Highlights

Flagship Formulas: Enfamil Infant Vs. Similac Advance

Enfamil Infant Formula

Similac Advance Infant Formula

Formula for Spit-Up: Enfamil A.R. Vs. Similac for Spit-Up Infant Formula

Enfamil A.R.

Similac for Spit-Up Infant Formula

Gentle Formulas: Enfamil NeuroPro Gentlease vs. Similac Pro-Sensitive

Enfamil NeuroPro Gentlease Infant Formula

Similac Pro-Sensitive Infant Formula

Formula for Babies with Allergies: Enfamil Nutramigen vs. Similac Alimentum

Enfamil Nutramigen With Enflora LGG Powder Infant Formula

Similac Alimentum

Formula for Premature Babies: Enfamil NeuroPro Enfacare vs. Similac NeoSure

Enfamil NeuroPro Enfacare

Similac NeoSure

Lactose-Free, Non-Dairy Soy Formula: Enfamil ProSobee vs. Similac Soy Isomil

Enfamil ProSobee

Similac Soy Isomil

Which One Is Better Similac Or Enfamil?

Formula FAQs

Why Is Similac Bad For You?

Is It Bad To Switch From Similac To Enfamil?

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