Fertility

Similac Or Enfamil: Which Formula Is The Right One For Your Baby?

Updated on 24 June 2022 • 18 minute read

 

Overview 

Different formula brands offer various products to meet each baby’s specific nutrition requirements. Finding the best formula can be a big challenge for many parents, but some stick to popular name brands like Similac or Enfamil.

Still, there’s no perfect formula that can meet the needs of all children.

In choosing the right formula for your little one, you have to consider its ingredients and other contents versus what your baby needs and possible food sensitivities or allergies.

Similac uses more added sugars in your baby’s formula. It may be a more budget-friendly option but Enfamil has more natural ingredients and less sugar. For many moms, that can be the deciding factor.

So, what formulas do Similac and Enfamil offer? Are there special formula options for specific medical conditions? Which formula should you pick for your baby? Are there any formula recalls on these products? Find out below.

But make sure you consult with your little one’s pediatrician, no matter which brand or type of formula you pick for your child.

 

Enfamil Products

Everyday Nutrition

  • Enfamil NeuroPro Infant Formula
  • Enfamil Enspire Infant Formula
  • Enfamil Simply Organic Infant Formula
  • Enfamil Premium A2 Infant Formula
  • Enfamil Infant Formula
  • Enfagrow NeuroPro Toddler Nutritional Drink
  • Enfagrow Premium Toddler Nutritional Drink
  • Enfagrow Enspire Toddler Nutritional Drink
  • Enfagrow Premium Transitions Infant & Toddler Formula
  • Enfagrow Toddler Next Step Milk Drink

 

Special Dietary Needs

For Premature Babies

  • Enfamil NeuroPro EnfaCare Infant Formula
  • Enfamil Premature Infant Formula

 

Tummy Troubles (Gas, Fussiness, Crying, Colic, Or Spit-Up)

  • Enfamil NeuroPro Gentlease Infant Formula
  • Enfamil NeuroPro Sensitive Infant Formula
  • Enfamil Enspire Gentlease Infant Formula
  • Enfamil A.R. Infant Formula
  • Enfamil Reguline Infant Formula
  • Enfamil ProSobee Infant Formula
  • Enfamil Gentlease Infant Formula
  • Enfagrow Premium Gentlease Toddler
  • Enfagrow Toddler Transitions Gentlease Infant & Toddler Formula

 

Cow’s Milk Allergies & Other Food Allergies

  • Enfamil Nutramigen with Enflora LGG Powder Infant Formula
  • Nutramigen with Enflora LGG Toddler Formula
  • PurAmino Hypoallergenic Infant Formula

 

Other Special Formulas

  • Pregestimil Infant Formula (trouble absorbing fats)
  • Enfamil Reguline (constipation)

 

Similac Products

Everyday Nutrition

  • Similac 360 Total Care Infant Formula
  • Similac Advance Infant Formula
  • Similac Pro-Advance Infant Formula
  • Similac Organic
  • Similac Organic with A2 Milk Infant Formula
  • Similac for Supplementation (to supplement breastfeeding)
  • Similac Pure Bliss (Non-GMO)
  • Go & Grow by Similac Milk-Based Toddler Drink
  • Go & Grow by Similac Toddler Drink with 2’-FL HMO for Immune Support
  • Pure Bliss by Similac Toddler Drink
  • Similac Organic Toddler Drink with A2 Milk

 

Special Dietary Needs

For Premature Babies

  • Similac NeoSure Infant Formula

 

Tummy Troubles (Gas, Fussiness, Crying, Colic, Or Spit-Up)

  • Similac 360 Total Care Sensitive Infant Formula
  • Similac Pro-Total Comfort Infant Formula
  • Similac Sensitive
  • Similac Pro-Sensitive
  • Similac Soy Isomil
  • Similac for Spit-Up
  • Go & Grow by Similac Sensitive Toddler Drink

 

Cow’s Milk Allergies & Other Food Allergies

  • Similac Alimentum Hypoallergenic Infant Formula
  • Similac EleCare

 

Other Special Formulas

  • Similac Advance Lamehadrin (Badatz Kosher certified formula, a special kosher certificate)

 

Enfamil Vs Similac: Main Similarities & Differences 

Similarities

Pros

  • Both brands offer a wide range of infant products, including non-dairy, lactose-free, soy-based, or hypoallergenic formulas. (1-4)
  • Both have non-GMO formulas
  • GMOs (genetically modified organisms) may cause autoimmunity, allergies, neurological disorders, autism, ADHD (attention deficit hyperactivity disorder), endocrine disruption, and growth failure. (5) 
  • Both brands meet the infant formula requirements of the FDA (Food and Drug Administration) and may be safe for babies. (6)
  • Both brands contain choline, a nutrient that can help metabolize or digest fats (7)
  • Both have vitamin K, an important vitamin for bone metabolism that may also have anti-cancer effects (8)
  • Both contain DHA (docosahexaenoic acid), lutein, and vitamin E, which can support your baby’s brain and eye development (9)(10)(11)
  • Both have ARA (arachidonic acid), which is a special nutrient found in breast milk that can promote a healthier immune system, and muscle repair and growth (9)
  • Most formulas also contain taurine (may play a role in brain development) and nucleotides (may promote immune response) (12)(13)
  • Loyalty programs: Enfamil Family Beginnings Program and Similac StrongMoms Rewards 

 

Cons

  • Most of the products from both brands contain soy oil. Although highly refined soy oil may be allergen-free, you might still want to keep an eye on this ingredient, especially if your child has soy allergies. (14)
  • They contain processed vegetable oils, which can contain unhealthy trans fats that may lead to a higher risk of developing coronary heart diseases (15)
  • Most products are non-organic
  • These formulas can still be safe for consumption, but some parents prefer organic formulas, which may be a healthier alternative.
  • Organic formulas and foods may have the same nutritional values as non-organic options. But they may reduce the risk of eczema in infants, obesity, and certain cancers, such as non-Hodgkin lymphoma. (16)

Differences 

Between the two brands, the different products also have different features. But these are their main differences:

 

Enfamil Highlights

  • May use less sugar

 

Similac Highlights

  • Most Similac formulas cost less than Enfamil (when comparing similar products)
  • Usually has higher levels of linoleic acid
  • Studies show that this fatty acid may help promote growth and development, especially in preterm babies. (17)
  • Similac formulas may be free from palm olein oil, a common ingredient in formulas that can reduce calcium absorption. (18)

 

Similac Vs. Enfamil: Comparison Of Similar Products

Flagship Formulas

  • Basic milk products that can provide nutrition for your baby in the first year of their life
  • Milk-based ingredients (whey protein, lactose, and nonfat milk)
  • Similar mixture of oils (coconut oil, soy oil, and high oleic safflower oil).
  • Prebiotics, which can help promote a healthy gut (19)
  • Free from added sugars, maltodextrin, and corn syrups (20)(21)

 

Enfamil Infant Highlights

  • Contains two types of prebiotics; Similac Advance has only one
  • Doesn’t have a recall
  • More carbohydrates, folic acid, and vitamin E

 

Similac Advance Highlights

  • Cheaper ($26.99 for a 23.2 oz can or $1.31 per oz) than Enfamil Infant ($28.49 for a 21.1 oz can or $1.35 per oz)
  • More proteins, fats, and linoleic acid

 

Formulas For Spit-Up

  • Formulated for babies who may spit up a lot
  • Rice starch for a thicker formulation

 

Enfamil A.R. Highlights

  • Free from corn syrup and added sugars
  • Dual prebiotics for better gut health (19)
  • More carbohydrates, proteins, folic acid, and vitamins D and E

 

Similac for Spit-Up Highlights

  • Costs less ($28.99 for a 19.5 oz tub or $1.49 per oz) than Enfamil A.R. ($31.99 for a 19.5 oz tub or $1.64 per oz)
  • Non-GMO formula
  • More fat content, calcium, and linoleic acid

 

Gentle Formulas

  • Formulated for fussiness and gas
  • Both contain corn syrup solids

 

Enfamil NeuroPro Gentlease Highlights

  • MFGM (milk fat globule membrane), which can promote neurodevelopment and defense against infections (22)
  • More proteins, folic acid, and vitamin E

 

Similac Pro-Sensitive Highlights 

  • Costs less ($29.99 for a 20.1 oz tub or $1.49 per oz) than Enfamil Neuropro Gentlease ($29.99 for a 19.5 oz tub or $1.54 per oz)
  • Prebiotics for a healthier gut (19)
  • More fat content, carbohydrates, calcium, and linoleic acid

 

Formulas For Babies With Allergies

  • Formulated for babies with hypersensitivities or allergies to proteins in cow’s milk formula
  • Casein hydrolysate (smaller, broken-down proteins)

 

Enfamil Nutramigen Highlights

  • The brand claims that it can reduce the incidence of future allergies (such as asthma and allergic rhinitis) and may help your baby overcome a cow’s milk allergy.
  • Probiotics or friendly gut bacteria (23)
  • More carbohydrates, protein equivalent, folic acid, and choline

 

Similac Alimentum Highlights

  • Costs less ($38.88 for a 19.8 oz tub or $1.96 per oz) than Enfamil Nutramigen ($45.99 for a 19.8 oz tub or $2.32 per oz)
  • MCT oils (medium-chain triglycerides) that may be easier to absorb (24)
  • More calcium, total fats, vitamin E, and linoleic acid

 

Formula For Premature Babies

  • Formulated for premature babies
  • Easy-to-digest milk-based formulas
  • Can promote better immune health
  • Free from palm oil, which can affect calcium absorption (18)

 

Enfamil NeuroPro Highlights

  • MFGM (milk fat globule membrane), which can promote brain development and a healthier immune system (22) 
  • More carbohydrates, calcium, folic acid, choline, linoleic acid, and vitamins A, D, and E

 

Similac Neosure

  • Costs less ($26.1 for a 22.8 oz tub or $1.15 per oz) than Enfamil NeuroPro ($33.99 for a 23 oz tub or $1.48 per oz)
  • Free from artificial growth hormones (25)
  • More fat content

 

Lactose-Free, Non-Dairy Soy Formulas

  • Lactose-free soy proteins
  • Formulated for babies with milk protein allergies
  • May be given to babies with galactosemia (a condition that prevents your baby’s body from properly digesting the simple sugar galactose, a component of larger sugar lactose) (4)
  • Alternative formulas if your baby’s tummy is sensitive to milk proteins
  • Corn syrup

 

Enfamil ProSobee Highlights

  • More carbohydrates, proteins, folic acid, and vitamin E

 

Similac Soy Isomil Highlights

  • Costs less ($33.3 for a 30.8 oz tub or $1.08 per oz) than Enfamil ProSobee ($31.99 for a 20.9 oz tub or $1.53 per oz)
  • Prebiotics for a healthier immune system (19)
  • More fat content and linoleic acid

 

Learn more about each formula below.

 

Flagship Formulas: Enfamil Infant Vs. Similac Advance

Enfamil Infant Formula

Price

  • 21.1 oz can: $28.49
  • 29.4 oz can: $37.49
  • 12.5 oz can: $18.49

 

Best Features & Safety

  • Complete nutrition for your baby’s first year
  • Choline and DHA (docosahexaenoic acid), which are important nutrients for your baby’s brain development (9)
  • Dual-prebiotics blend (galactooligosaccharides and polydextrose) to support your baby’s immune system (19)
  • Free from added sugars, maltodextrin, and corn syrups.

 

Product Recall

  • None

 

Cons

  • Palm olein oil, soy oil, and other questionable processed vegetable oils (14)(15)(18)
  • Potential allergens: soy lecithin and milk (2)(26)

 

Ingredients

  • Nonfat milk
  • Lactose
  • Vegetable oil (palm olein, soy, coconut, and high oleic sunflower oils)
  • Whey protein concentrate
  • GOS (galactooligosaccharides) prebiotics
  • Polydextrose prebiotics
  • Mortierella alpina oil (ARA source)
  • Crypthecodinium cohnii oil (DHA source)
  • Lutein
  • Soy lecithin
  • Nucleotides
  • Taurine

 

Nutritional Facts

Each serving (5 fl oz, 100 calories) contains:

  • Total fats: 5.3 g
  • Total carbohydrates: 11.3 g
  • Proteins: 2 g
  • Iron: 1.8 mg
  • Calcium: 78 mg
  • Folic acid: 16 mcg
  • Choline: 24 mg
  • Vitamin A: 300 IU
  • Vitamin D: 60 IU
  • Vitamin E: 2 IU
  • Linoleic acid: 800 mg

 

What Customers Say

My daughter loves this milk… no issues at all and we are happy to have enfamil.” – Reviewer on Enfamil’s website.

This gave my first daughter really bad acid reflux. Now its the same for my second daughter.” – Reviewer on Enfamil’s website.

 

Similac Advance Infant Formula

Price

  • 20.6 oz tub: $26.99

 

Best Features & Safety

  • Nutritionally complete, iron-fortified milk-based infant formula for your baby’s first year
  • Free from palm oil, which can reduce calcium absorption (18)
  • Blend of DHA, lutein, and vitamin E, which can support your baby’s brain and eye development (9)(10)(11)
  • Free from artificial growth hormones that may be linked to certain cancers. (25)
  • Kosher and halal
  • Prebiotic FOS (fructooligosaccharides) for a healthier immune system and gut health (19)
  • Free from added sugars, maltodextrin, and corn syrup

 

Product Recall

  • Similac Advance (powder formula) was included in the 2010 Similac recall due to the possible contamination with the small common beetle. (27)
  • According to the FDA’s recall advisory, ingesting the beetle larvae or insect parts may not pose a significant health risk. But it can cause intestinal discomfort, and your child might refuse to eat. (27)
  • In 2006, Similac Advance (liquid, ready-to-drink formula) was recalled because the bottles had a manufacturing defect. Due to a lacking layer in the bottle, the contents may react with air and have a reduced amount of vitamin C. (28)
  • In 2005, Similac Advance with Iron (powder formula) was also recalled due to the possible contamination with polyvinyl chloride plastic particles. It was attributed to a manufacturing issue. (29)

 

Cons

  • It had recalls. 
  • Potential allergens: milk and soy 
  • Soy oil and other processed vegetable oils 

 

Ingredients

  • Nonfat milk
  • Lactose
  • High oleic safflower oil
  • Whey protein concentrate
  • Soy oil
  • Coconut oil
  • C. cohnii oil (DHA source)
  • M. alpina oil (ARA source)
  • Short-chain fructooligosaccharide prebiotics
  • Lutein
  • Soy lecithin
  • Taurine
  • Nucleotides

 

Nutritional Facts

Each serving (5 fl oz, 100 calories) contains:

  • Total fats: 5.6 g
  • Total carbohydrates: 10.5 g
  • Proteins: 2.07 g
  • Iron: 1.8 mg
  • Calcium: 78 mg
  • Folic acid: 15 mcg
  • Choline: 24 mg
  • Vitamin A: 300 IU
  • Vitamin D: 60 IU
  • Vitamin E: 1.5 IU
  • Linoleic acid: 1,000 mg

 

What Customers Say

I love this milk because it does not cause cramps in my son.” – Reviewer on Similac’s website.

It is difficult for baby to digest Similac Advance. Frequency increased for vometting whatever baby drinks.” – Reviewer on Similac’s website.

 

Formula for Spit-Up: Enfamil A.R. Vs. Similac for Spit-Up Infant Formula

Enfamil A.R.

Price

  • 19.5 oz tub: $31.99
  • 12.9 oz can: $21.99

 

Best Features & Safety

  • Complete nutrition for your baby’s first year
  • Enfamil claims that it’s clinically proven to reduce spit-up by more than 50% in one week.
  • DHA, which can help support your baby’s brain development (9)
  • Dual prebiotics (galactooligosaccharides and polydextrose), which may promote better digestive and immune health (19)
  • Meets reflux reduction guidelines (thickened formula) set by the AAP (American Academy of Pediatrics) (30)
  • Free from corn syrup and added sugars

 

Product Recall

  • None

 

Cons

  • Palm olein oil, soy oil, and processed vegetable oils (14)(15)(18)
  • Maltodextrin, which may cause colic, gas, bloating, green stools, and possible intestinal injury (20)
  • Potential allergen: milk (2)
  • Rice starch (used as a thickening agent); although starches are considered safe by the AAP, there’s public pressure to remove this ingredient from any baby food (31)

 

Ingredients

  • Nonfat milk
  • Vegetable oil (palm olein, soy, coconut, and high oleic sunflower oils)
  • Rice starch
  • Lactose
  • Maltodextrin
  • GOS (galactooligosaccharides) prebiotics
  • Polydextrose prebiotics
  • Mortierella alpina oil (ARA source)
  • Crypthecodinium cohnii oil (DHA source)
  • Taurine

 

Nutritional Facts

Each serving (5 fl oz, 100 calories) contains:

  • Total fats: 5.1 g
  • Total carbohydrates: 11.3 g
  • Proteins: 2.5 g
  • Iron: 1.8 mg
  • Calcium: 78 mg
  • Folic acid: 16 mcg
  • Choline: 24 mg
  • Vitamin A: 300 IU
  • Vitamin D: 60 IU
  • Vitamin E: 2 IU
  • Linoleic acid: 780 mg

 

What Customers Say

Only thing my newborn is able to keep down without throw up/spit up!” – Reviewer on Enfamil’s website.

I bought this for my daughter since she has acid reflux and it was recommended by her doctor and she was severely constipated to the point where she was throwing up from trying to go.” – Reviewer on Enfamil’s website.

 

Similac for Spit-Up Infant Formula

Price

  • 19.5 oz tub: $28.99

 

Best Features & Safety

  • The brand claims that it’s clinically proven to reduce spit-up frequency by 54% in healthy infants.
  • Non-GMO formula
  • Easy-to-digest formula that may be suitable for babies with lactose sensitivity
  • Exclusive blend of DHA, lutein, and vitamin E that may support your baby’s brain and eye development (9)(10)(11)
  • Free from palm olein oil, which can affect calcium absorption (18)
  • Free from artificial growth hormones (25)
  • Doesn’t have maltodextrin

 

Product Recall

  • None

 

Cons

  • Rice starch as a thickening agent; starches are considered safe by the AAP, but many are calling for its removal as an ingredient of baby food (31)
  • Soy oil and processed vegetable oils.
  • Added sugars and corn syrup
  • Potential allergen: milk

 

Ingredients

  • Corn syrup
  • Rice starch
  • Milk protein isolate
  • Sugar
  • High oleic safflower oil, soy oil, and coconut oil
  • GOS (galactooligosaccharides) prebiotics
  • C. cohnii oil (DHA source)
  • M. alpina oil (ARA source)
  • Lutein
  • Taurine
  • Nucleotides

 

Nutritional Facts

Each serving (5 fl oz, 100 calories) contains:

  • Total fats: 5.4 g
  • Total carbohydrates: 11 g
  • Proteins: 2.1 g
  • Iron: 1.8 mg
  • Calcium: 84 mg
  • Folic acid: 15 mcg
  • Choline: 24 mg
  • Vitamin A: 300 IU
  • Vitamin D: 50 IU
  • Vitamin E: 1.5 IU
  • Linoleic acid: 1,000 mg

 

What Customers Say

Hallelujah, after buying this formula all the screaming stopped, we have one very content baby, no spitting up and longer uninterrupted naps, an absolute blessing.” – Reviewer on Similac’s website.

It did reduce my 6 month old spit ups, but her bowl movements have reduced and she started gaining weight immediately. The weight gain may be due to the sugar ingredient.” – Reviewer on Similac’s website.

 

Gentle Formulas: Enfamil NeuroPro Gentlease vs. Similac Pro-Sensitive 

Enfamil NeuroPro Gentlease Infant Formula

Price

  • 19.5 oz tub: $29.99

 

Best Features & Safety

  • Complete nutrition for your baby’s first year
  • The brand claims that this formula can provide all-in-one digestive comfort in 24 hours
  • May reduce fussiness, crying, gas, and spit-up
  • Easy-to-digest proteins
  • MFGM (milk fat globule membrane), which can promote neurodevelopment and defense against infections (22) 
  • DHA and ARA, which can promote your baby’s brain development healthier immune system (9)
  • Free from added sugars and maltodextrin

 

Product Recall

  • None

 

Cons

  • Corn syrup, soy oil, palm oil, and processed vegetable oils

 

Ingredients

  • Corn syrup solids
  • Partially hydrolyzed nonfat milk
  • Whey protein concentrate solids (soy)
  • Vegetable oil (palm olein, soy, coconut, and high oleic sunflower oils)
  • Whey protein-lipid concentrate, a source of MFGM
  • Mortierella alpina oil (ARA source)
  • Schizochytrium sp. oil (DHA source)
  • Taurine

 

Nutritional Facts

Each serving (5 fl oz, 100 calories) contains:

  • Total fats: 5.3 g
  • Total carbohydrates: 10.8 g
  • Proteins: 2.3 g
  • Iron: 1.8 mg
  • Calcium: 82 mg
  • Folic acid: 16 mcg
  • Choline: 24 mg
  • Vitamin A: 300 IU
  • Vitamin D: 60 IU
  • Vitamin E: 2 IU
  • Linoleic acid: 780 mg

 

What Customers Say

My son was very gassy and fussy in the beginning and we started using this and it has helped a lot.” – Reviewer on Enfamil’s website.

This caused her to have way more spit up, more gass/fussiness and gray green colored poop.” – Reviewer on Enfamil’s website.

 

Similac Pro-Sensitive Infant Formula

Price

  • 20.1 oz tub: $29.99

 

Best Features & Safety

  • May help reduce fussiness or gas due to lactose sensitivity for babies with sensitive tummies
  • 2’-FL HMO (human milk oligosaccharide), a prebiotic abundant in breast milk that may support your baby’s developing immune system (19)
  • DHA, lutein, and vitamin E blend to help promote your baby’s brain and eye development (9)(10)(11)
  • Free from palm olein oil, which can affect calcium absorption (18)
  • Free from artificial growth hormones
  • Non-GMO formula
  • Doesn’t have maltodextrin

 

Product Recall

  • None

 

Cons

  • Corn syrup, soy oil, and processed vegetable oils
  • Added sugars
  • Potential allergens: milk and soy lecithin

 

Ingredients

  • Corn syrup
  • Milk protein isolate
  • Sugar
  • High oleic safflower oil, soy oil, and coconut oil
  • C. cohnii oil (DHA source)
  • M. alpina oil (ARA source)
  • 2’-fucosyllactose, short-chain fructooligosaccharides (prebiotics)
  • Lutein
  • Soy lecithin
  • Nucleotides

 

Nutritional Facts

Each serving (5 fl oz, 100 calories) contains:

  • Total fats: 5.4 g
  • Total carbohydrates: 10.9 g
  • Proteins: 2.1 g
  • Iron: 1.8 mg
  • Calcium: 84 mg
  • Folic acid: 15 mcg
  • Choline: 24 mg
  • Vitamin A: 300 IU
  • Vitamin D: 60 IU
  • Vitamin E: 1.5 IU
  • Linoleic acid: 1,000 mg

 

What Customers Say

This is the only formula that works for my LO who is now 11 months old.” – Reviewer on Amazon.

This particular similar formula has been awful for my baby. It gave her more gas, made her so fussy, and the poor thing could not sleep well EVER.” – Reviewer on Similac’s website.

 

Formula for Babies with Allergies: Enfamil Nutramigen vs. Similac Alimentum

Enfamil Nutramigen With Enflora LGG Powder Infant Formula

Price

  • 27.8 oz can: $58.99
  • 19.8 oz can: $45.99
  • 12.6 oz can: $34.99

 

Best Features & Safety

  • Hypoallergenic formula made with extensively hydrolyzed (broken-down) proteins that may be less likely to trigger an allergic response
  • Lactose-free formula
  • The brand claims that it’s clinically proven to reduce colic because of cow’s milk allergy within 48 hours.
  • The brand also claims that this may help reduce the incidence of future allergies, such as asthma, eczema, allergic rhinitis, and hives.
  • According to the brand, this formula may also help your baby overcome a cow’s milk allergy and return to a regular formula within six months of feeding, compared with the Enfamil Nutramigen formula without Enflora LGG.
  • DHA and ARA, which are nutrients in breast milk that may support your baby’s brain and eye development (9)
  • Lactobacillus rhamnosus (probiotic cultures), which can promote a healthier gut (23)
  • Free from added sugars and maltodextrin

 

Product Recall

  • In 2001, Enfamil Nutramigen was recalled due to incorrect preparation instructions printed on the label. Following these instructions may lead to serious health problems, possibly even death. (32)(33)

 

Cons

  • It had a recall.
  • Corn syrup, palm oil, soy oil, modified corn starch, and processed vegetable oils

 

Ingredients

  • Corn syrup solids
  • Vegetable oil (palm olein, soy, coconut, and high oleic sunflower oils)
  • Casein hydrolysate (milk)
  • Modified corn starch
  • Mortierella alpina oil (ARA source)
  • Schizochytrium sp. oil (DHA source)
  • Lactobacillus rhamnosus (probiotic cultures)
  • Taurine

 

Nutritional Facts

Each serving (5 fl oz, 100 calories) contains:

  • Total fats: 5.3 g
  • Total carbohydrates: 10.3 g
  • Protein equivalent: 2.8 g
  • Iron: 1.8 mg
  • Calcium: 94 mg
  • Folic acid: 16 mcg
  • Choline: 24 mg
  • Vitamin A: 300 IU
  • Vitamin D: 60 IU
  • Vitamin E: 2 IU
  • Linoleic acid: 780 mg

 

What Customers Say

I just started my 5 week old on this because we found out she had an cow allergy and it worked so fast . she stopped spitting up and being fussy.” – Reviewer on Enfamil’s website.

My daughter started having really bad acid reflux and did not want to drink her bottles.” – Reviewer on Amazon.

 

Similac Alimentum

Price

  • 19.8 oz can: $38.88

 

Best Features & Safety

  • Hypoallergenic formula for babies up to 12 months old with food allergies and colic symptoms due to protein sensitivity
  • The brand claims that it’s clinically proven to reduce excessive crying because of cow’s milk protein sensitivity within 24 hours.
  • Lactose-free formula
  • DHA and ARA, which are special nutrients found in breast milk that can support brain and eye development (9)
  • Broken-down proteins that may be easier to digest for babies with food allergies
  • MCT oils (medium-chain triglycerides), which may be easier to absorb and suitable for lactose sensitivity (24)
  • Free from palm olein oil, which can reduce calcium absorption (18)

 

Product Recall

  • In 2006, Similac Alimentum liquid ready-to-drink formula was recalled due to a missing layer in the bottle caused by a manufacturing error. The absence of this layer causes air to get in the bottle and react with its content, leading to a reduced vitamin C content. (28)

 

Cons

  • Added sugars, corn maltodextrin, soy oil, and processed vegetable oils
  • Xanthan gum; though JECFA (Joint FAO/WHO Expert Committee on Food Additives) considers it safe as a stabilizer to infant formula, it may cause gas, bloating, or flu-like symptoms (34)(35)
  • The liquid formulation had a recall

 

Ingredients

  • Corn maltodextrin
  • Casein hydrolysate (broken-down milk proteins) derived from milk
  • Sugar
  • High oleic safflower oil
  • Medium-chain triglycerides
  • Soy oil
  • C. cohnii oil (DHA source)
  • M. alpina oil (ARA source)
  • Xanthan gum
  • Taurine

 

Nutritional Facts

Each serving (5 fl oz, 100 calories) contains:

  • Total fats: 5.54 g
  • Total carbohydrates: 10.2 g
  • Protein equivalent: 2.75 g
  • Iron: 1.8 mg
  • Calcium: 105 mg
  • Folic acid: 15 mcg
  • Choline: 12 mg
  • Vitamin A: 300 IU
  • Vitamin D: 60 IU
  • Vitamin E: 3 IU
  • Linoleic acid: 800 mg

 

What Customers Say

Alimentum is the only formula that my infant can tolerate due to both a milk protein allergy and a corn allergy.” – Reviewer on Similac’s website.

My first impression was that this stuff smells really bad. I couldn’t tell you if this works or not because my baby HATED the taste.” – Reviewer on Walmart.

 

Formula for Premature Babies: Enfamil NeuroPro Enfacare vs. Similac NeoSure

Enfamil NeuroPro Enfacare

Price

  • 13.6 oz can: $23.99
  • 23 oz can: $33.99

 

Best Features & Safety

  • Formulated for premature babies
  • Recommended for use up to nine months of age
  • The brand claims that it’s clinically proven to promote catch-up growth similar to full-term breastfed babies.
  • Milk-based formula with enriched nutrition from DHA and ARA to help support your baby’s immune system and brain development (9)
  • MFGM (milk fat globule membrane), which can also promote neurodevelopment and defense against infections (22)
  • Free from palm olein oil, which can reduce calcium absorption (18)

 

Product Recall

  • None

 

Cons

  • Maltodextrin, soy oil, and processed vegetable oils
  • Potential allergens: milk and soy lecithin

 

Ingredients

  • Water
  • Nonfat milk
  • Maltodextrin
  • Lactose
  • Whey protein concentrate
  • High oleic sunflower oil
  • Soy oil
  • MCT oil (medium chain triglycerides)
  • Whey
  • Protein-lipid concentrate
  • Coconut oil
  • Mortierella alpina oi (ARA source)
  • Schizochytrium sp. oil (DHA oil)
  • Soy lecithin
  • Carrageenan
  • Nucleotides
  • Taurine

 

This product contains carrageenan. Although there’s some public concern over this ingredient, OB-GYN and Maternal-Fetal Medicine Dr. Kecia Gaither and the FDA assure parents that it can be a safe additive to baby formula. (36)(37)

 

Nutritional Facts

Each serving (4.5 fl oz, 100 calories) contains:

  • Total fats: 5.3 g
  • Total carbohydrates: 10.4 g
  • Proteins: 2.8 g
  • Iron: 1.8 mg
  • Calcium: 120 mg
  • Folic acid: 26 mcg
  • Choline: 24 mg
  • Vitamin A: 450 IU
  • Vitamin D: 75 IU
  • Vitamin E: 4 IU
  • Linoleic acid: 780 mg

 

What Customers Say

I got this when my premie weighed 4lb 11oz and within 3 days he went up to 5lb 6oz! It’s truly helped our little guy!” – Reviewer on Enfamil’s website.

To harsh for my preemie, he threw up every time he was given enfacare for extra calories.” – Reviewer on Enfamil’s website.

 

Similac NeoSure

Price

  • 22.8 oz, case of four: $104.39 or $26.10 per can

 

Best Features & Safety

  • May provide complete nutrition for babies born prematurely
  • More protein, vitamins, and minerals than standard infant formula to promote catch-up growth
  • Unique blend of DHA, lutein, and vitamin E that may support brain and eye development (9)(10)(11)
  • More calcium and phosphorus for your baby’s growing bones
  • Free from artificial growth hormones and palm olein oil (may reduce calcium absorption) (18)

 

Product Recall

  • None

 

Cons

  • Corn syrup, soy oil, and processed vegetable oils
  • Potential allergens: milk and soy lecithin

 

Ingredients

  • Nonfat milk
  • Corn syrup solids
  • Lactose
  • Soy oil
  • High oleic safflower oil
  • Whey protein concentrate
  • MCT oil (medium chain triglycerides)
  • Coconut oil
  • C. cohnii oil (DHA source)
  • M. alpina oil (ARA source)
  • Lutein
  • Soy lecithin
  • Taurine
  • Nucleotides

 

Nutritional Facts

Each serving (4.5 fl oz, 100 calories) contains:

  • Total fats: 5.5 g
  • Total carbohydrates: 10.1 g
  • Proteins: 2.8 g
  • Iron: 1.8 mg
  • Calcium: 105 mg
  • Folic acid: 25 mcg
  • Choline: 16 mg
  • Vitamin A: 350 IU
  • Vitamin D: 70 IU
  • Vitamin E: 3.6 IU
  • Linoleic acid: 750 mg

 

What Customers Say

Helped him gain the weight he needed to leave the NICU after 6 days and come home.” – Reviewer on Similac’s website.

Since we switched to neosure she is so uncomfortable and at times miserable and burns all the extra calories trying to pass gas and poop.” – Reviewer on Similac’s website.

 

Lactose-Free, Non-Dairy Soy Formula: Enfamil ProSobee vs. Similac Soy Isomil

Enfamil ProSobee

Price

  • 12.9 oz can: $21.99
  • 20.9 oz can: $31.99

 

Best Features & Safety

  • Soy-based, lactose-free alternative to milk-based formulas
  • May help ease fussiness and gas caused by sensitivity to dairy-based formulas
  • Can be ideal for vegetarian or Kosher diets
  • Comparable amount of DHA as standard, dairy Enfamil formulas
  • DHA and ARA, which may help with your baby’s brain and immune system function (9)

 

Product Recall

  • None

 

Cons

  • Corn syrup, soy oil, palm olein oil, and processed vegetable oils
  • Potential allergen: soy protein

 

Ingredients

  • Corn syrup solids
  • Vegetable oil (palm olein, soy, coconut, and high oleic sunflower oils)
  • Soy protein isolate
  • Mortierella alpina oil (ARA source)
  • Crypthecodinium cohnii oil (DHA source)
  • Taurine

 

Nutritional Facts

Each serving (5 fl oz, 100 calories) contains:

  • Total fats: 5.3 g
  • Total carbohydrates: 10.6 g
  • Proteins: 2.5 g
  • Iron: 1.8 mg
  • Calcium: 105 mg
  • Folic acid: 16 mcg
  • Choline: 24 mg
  • Vitamin A: 300 IU
  • Vitamin D: 60 IU
  • Vitamin E: 2 IU
  • Linoleic acid: 800 mg

 

What Customers Say

Love the product since we are vegetarian this was a good formula too use since I was not able to breastfeed my first baby.” – Reviewer on Enfamil’s website.

Made my baby vomit all night. Do not recommended at all.” – Reviewer on Enfamil’s website.

 

Similac Soy Isomil

Price

  • 30.8 oz, case of four: $133.19 or $33.30 per can

 

Best Features & Safety

  • Nutritionally complete soy-based formula that may be easier to digest by infants with sensitive tummies
  • May help relieve fussiness and gas
  • Special formula for babies with lactose intolerance and galactosemia (4)
  • The brand claims that it’s the only soy formula clinically proven to help support your baby’s developing immune system like dairy-based formulas.
  • Can be suitable for vegetarian diets
  • Prebiotic FOS (fructooligosaccharides) that may help support a healthy gut and immune system (19)
  • DHA, lutein, and vitamin E, which are special ingredients in breast milk that may support your baby’s brain and eye development (9)(10)(11)
  • Free from palm oil, which can reduce calcium absorption (18)

 

Product Recall

  • None

 

Cons

  • Corn syrup, soy oil, and processed vegetable oils
  • Added sugars

 

Ingredients

  • Corn syrup solids
  • Soy protein isolate
  • High oleic safflower oil
  • Sugar
  • Soy oil
  • Coconut oil
  • C. cohnii oil (DHA source)
  • M. alpina oil (ARA source)
  • Lutein
  • Short-chain fructooligosaccharides (prebiotics)
  • Taurine
  • Lycopene

 

Nutritional Facts

Each serving (5 fl oz, 100 calories) contains:

  • Total fats: 5.46 g
  • Total carbohydrates: 10.4 g
  • Proteins: 2.45 g
  • Iron: 1.8 mg
  • Calcium: 105 mg
  • Folic acid: 15 mcg
  • Choline: 24 mg
  • Vitamin A: 300 IU
  • Vitamin D: 60 IU
  • Vitamin E: 1.5 IU
  • Linoleic acid: 1,000 mg

 

What Customers Say

I switched to this lactose free option 5 days ago and my baby has not spit up at all.” – Reviewer on Similac’s website.

This formula did not work for our 4-month old as he would throw it all up about an hour after he ate it.” – Reviewer on Similac’s website.

 

Which One Is Better Similac Or Enfamil?

Choose Enfamil formulas if:

  • You prefer a brand with more natural ingredients and less sugar
  • You don’t mind the higher price tag

 

Choose Similac formulas if:

  • You prefer a more budget-friendly option
  • You don’t mind having more added sugars in your baby’s formula
  • You’re looking for products with higher levels of linoleic acid, which can promote growth and development, especially in preterm babies (17)
  • You prefer formulas free from palm olein oil so your baby can absorb more calcium necessary for bone development (18)

 

Formula FAQs

Which Baby Formula Is Best?

The best baby formula may depend on what your child needs. Here are some of our recommendations:

 

Traditional & Regular Formulas With Special Ingredients

  • Enfamil Enspire
  • Similac Advance

 

Non-Dairy, Soy Formulas

  • Similac Soy Isomil
  • Enfamil ProSobee

 

Organic Infant Formulas

  • Earth’s Best Soy-Based Infant Formula
  • Happy Baby Organic Formula

 

Soy-Free Formulas

  • Else Plant-Based Complete Nutrition for Toddlers
  • Baby’s Only Organic Pea Protein Formula

 

Why Is Similac Bad For You?

Because Similac is cheaper than Enfamil, it might seem like the better option.

But note that Similac may be using more sugars than Enfamil

Corn syrup and other added sugars may increase your baby’s appetite and promote obesity. (21)

So, you should consider each formula’s ingredients and nutritional values before making your choice.

And be sure to also ask for your pediatrician’s approval before switching to any new formula.

 

Is It Bad To Switch From Similac To Enfamil?

Despite having some differences, formulas of the same type might have similar contents. So, switching between the brands might not make a huge difference, unless your child has sensitivities to the components of the other formula.

Still, it’s important to check with your pediatrician before making the switch.

 

REFERENCES

(1) https://www.mayoclinic.org/diseases-conditions/lactose-intolerance/symptoms-causes/syc-20374232

(2) https://www.mayoclinic.org/diseases-conditions/milk-allergy/symptoms-causes/syc-20375101

(3) https://kidshealth.org/en/parents/soy-allergy.html

(4) https://www.childrenshospital.org/conditions-and-treatments/conditions/g/galactosemia/symptoms-and-causes

(5) https://www.greenamerica.org/blog/downsides-gmo-infant-formula-we-asked-pediatrician

(6) https://www.fda.gov/food/people-risk-foodborne-illness/questions-answers-consumers-concerning-infant-formula

(7) https://ods.od.nih.gov/factsheets/Choline-HealthProfessional/

(8) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600246/

(9) https://pubmed.ncbi.nlm.nih.gov/29413359/

(10) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6164534/

(11) https://kidshealth.org/en/kids/vitamin.html

(12) https://pubmed.ncbi.nlm.nih.gov/9635063/

(13) https://pubmed.ncbi.nlm.nih.gov/12410863/

(14) https://pubmed.ncbi.nlm.nih.gov/3894482/ 

(15) https://www.cfs.gov.hk/english/multimedia/multimedia_pub/multimedia_pub_fsf_85_01.html

(16) https://pubmed.ncbi.nlm.nih.gov/32519524/ 

(17) https://pubmed.ncbi.nlm.nih.gov/15825825/

(18) https://pubmed.ncbi.nlm.nih.gov/16582027/

(19) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615227/

(20) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940893/

(21) https://health.clevelandclinic.org/avoid-the-hidden-dangers-of-high-fructose-corn-syrup-video/

(22) https://pubmed.ncbi.nlm.nih.gov/27234413/

(23) https://www.healthychildren.org/English/ages-stages/baby/formula-feeding/Pages/Probiotics-in-Infant-Formula.aspx

(24) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209465/

(25) https://www.cancer.org/cancer/cancer-causes/recombinant-bovine-growth-hormone.html

(26) https://www.kidswithfoodallergies.org/soy-allergy.aspx

(27) https://www.reuters.com/article/us-abbott-idUSTRE68L4ZI20100922

(28) https://www.nytimes.com/2006/09/16/us/recall-of-infant-formula.html

(29) https://abcnews.go.com/Health/ParentingResourceCenter/similac-recall-bug-parts-baby-formula-worry-parents/story?id=11710959

(30) https://publications.aap.org/pediatrics/article/131/5/e1684/31266/Gastroesophageal-Reflux-Management-Guidance-for

(31) https://pubmed.ncbi.nlm.nih.gov/29762373/

(32) https://www.nytimes.com/2001/07/10/us/national-briefing-science-and-health-recall-of-baby-formula.html

(33) http://flca.info/HTMLobj-154/Recalls.pdf

(34) https://apps.who.int/food-additives-contaminants-jecfa-database/chemical.aspx?chemID=802

(35) https://www.npr.org/sections/health-shots/2011/05/23/136574547/fda-warns-against-food-thickener-for-premature-infants

(36) https://www.fda.gov/food/people-risk-foodborne-illness/questions-answers-consumers-concerning-infant-formula

(37) https://www.globenewswire.com/news-release/2019/02/07/1712386/0/en/Dr-Kecia-Gaither-Cautions-Mothers-on-Fables-and-Facts-with-Babies-Bottles-and-Booze.html

 

 

 

as seen on
We Got You, Mama.

Self-Care Rituals & Self-Love Practices To Support You & Your Family.

[gravityform id="6" title="false" description="false" ajax="true"]